Egzersiz Müdahalelerinin Gestasyonel Diyabet Üzerindeki Etkisi: Sistematik Derleme
DOI:
https://doi.org/10.5281/zenodo.8431098Anahtar Kelimeler:
Kan şekeri- Diyabet- Egzersiz- GebelikÖzet
Amaç: Gestasyonel diabetes mellitus (GDM) gebelik sırasında ortaya çıkan en yaygın metabolik hastalıktır ve son 20 yılda GDM oranlarının dünya genelinde önemli ölçüde arttığı gözlenmektedir. Hamilelik döneminde fiziksel olarak aktif olmanın fetüs ve anne için faydalı olduğu ve egzersizin GDM ile ilişkili görülebilecek olası komplikasyonları engellemede etkili olabileceği bildirilmiştir. Bu sistematik derlemenin amacı, gestasyonel diyabette egzersiz müdahalelerinin glisemik indeks, gebelik dönemi, obstetrik ve neonatal sonuçlar üzerindeki etkilerini değerlendirmektir. Bu çalışma, PRISMA-P (Preferred Reporting Items for Systematic review and Meta-Analysis Protocols) kılavuzuna göre hazırlanmıştır.
Materyal ve Metot: Çalışma kapsamına alınacak makaleler; Web of Science, Cochrane Library, PUBMED, Scopus ve Science Direct elektronik veri tabanlarında 2012-2022 yılları arasındaki makaleler taranmıştır. Taramalarda “gestational diabetes”, “exercise” ve “combined exercise”, ‘’pregnancy’’ or ‘’pregnant’’ ve ‘’diabetes’’ ve ‘’exercise’’ MeSH terimleri ile “gestasyonel diyabet” ve “egzersiz” ve “kombine egzersiz”, ‘’hamilelik’’ ya da ‘’hamile’’ ve ‘’diyabet’’ ve ‘’egzersiz’’ anahtar kelimeleri kullanılmış olup, klinik çalışmalar filtrelenmiştir.
Bulgular: Derlemeye 1228 GDM’li hamile kadın ile 9 randomize kontrollü çalışma dahil edilmiştir. Derlenen randomize kontrollü çalışmaların sonucunda, GDM tanısı almış gebelerde egzersiz müdahalesinin açlık kan şekeri seviyesinin 0.3-1.2 mmol, 2 saatlik tokluk kan şekeri seviyesinin de 0.2-0.5 mmol arasında değiştiği dolayısıyla egzersizin açlık ve tokluk kan şekeri seviyesi üzerinde etkili bir faktör olduğu bulunmuştur.
Sonuç: Bu sistematik derleme, GDM tanısı almış kadınların egzersiz müdahalesi ile glisemik yönetimi, insülin kullanımı, kan şekeri seviyesi, maternal ve neonatal dönemde glikoz intoleransına bağlı ortaya çıkabilecek komplikasyonların önlenmesinde ve gebelik döneminde fiziksel aktivite motivasyonunu iyileştirebileceğini önermektedir. Müdahaleler, doğum öncesi egzersiz müdahalesinin uzun vadeli faydalarını anlamak için doğum sonrası katılımcıları takip etmeyi amaçlamalıdır.
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